中国神经再生研究(英文版) ›› 2020, Vol. 15 ›› Issue (3): 450-452.doi: 10.4103/1673-5374.266056

• 观点:视神经损伤修复保护与再生 • 上一篇    下一篇

用于神经感觉视网膜细胞替代疗法的电-化学刺激

  

  • 出版日期:2020-03-15 发布日期:2020-05-26

Electro-chemotactic stimuli for cell replacement therapy in neurosensory retina

Maribel Vazquez   

  1. Department of Biomedical Engineering, Rutgers University: The State University of New Jersey, New Brunswick, NJ, USA
  • Online:2020-03-15 Published:2020-05-26
  • Contact: Maribel Vazquez, ScD,Maribel.vazquez@rutgers.edu.
  • Supported by:
    This work was supported by the US National Institutes of Health (NIH R21 EY026752).

摘要: orcid: 0000-0002-6184-3103 (Maribel Vazquez)

Abstract: Numbers of visually-impaired adults are rising rapidly around the globe. Neuronal transplantation therapies show great promise to restore vision, but have been severely impeded by poor synaptic positioning within retinal host. This perspectives article highlights our group’s abilities to remarkably direct the migration of transplantable cells by applying electro-chemical fields within retina-customized microtechnology. Integration of our in vitro results with current ex vivo and in vivo studies has the potential to transformatively impact outcomes of cell replacement therapy.