中国神经再生研究(英文版) ›› 2020, Vol. 15 ›› Issue (12): 2237-2238.doi: 10.4103/1673-5374.284984

• 观点:视神经损伤修复保护与再生 • 上一篇    下一篇

适应性视网膜神经节细胞功能:评估内部视网膜通路的自动调节

  


  • 出版日期:2020-12-15 发布日期:2020-08-04

Adaptable retinal ganglion cell function: assessing autoregulation of inner retina pathways

Tsung-Han Chou, Vittorio Porciatti   

  1. Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA
  • Online:2020-12-15 Published:2020-08-04
  • Contact: Vittorio Porciatti, DSc,vporciatti@med.miami.edu.
  • Supported by:
    This work was supported by the NIH-NEI RO1 EY019077, NIH center grant P30 EY014801, unrestricted grant to Bascom Palmer Eye Institute from Research to Prevent Blindness, Inc.

摘要: orcid: 0000-0002-1592-3532 (Vittorio Porciatti)

Abstract: RGCs are extremely high-maintenance neurons connecting the eye to the brain trough the optic nerve. In order to produce and propagate action potentials along the unmyelinated RGC axons and support axonal transport of materials back and forth from the eye to the brain, RGC require large amounts of energy. Therefore, RGCs are under considerable metabolic stress when healthy and become particularly vulnerable in disease, resulting in blindness