中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (2): 298-299.doi: 10.4103/1673-5374.290890

• 观点:脑损伤修复保护与再生 • 上一篇    下一篇

化学生物学–解锁神经化学表观遗传学的工具箱?

  

  • 出版日期:2021-02-15 发布日期:2020-12-02

Chemical biology: a toolbox to unlock neurochemical epigenetics?

Dennis Özcelik*   

  1. Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada
  • Online:2021-02-15 Published:2020-12-02
  • Contact: Dennis Özcelik, PhD, dennis.ozcelik@sund.ku.dk or dennis.oezcelik@googlemail.com.
  • Supported by:
    This work was supported in part by a postdoctoral fellowship from the Canadian Institutes of Health Research (CIHR) to DÖ.

摘要: https://orcid.org/0000-0002-7185-4690 (Dennis Özcelik)

Abstract: The complex challenges of studying neurochemistry: Neurochemistry comprises the molecular and biochemical roles of a vast variety of chemical compounds, including amino acids, peptides, gaseous molecules, and small molecules such as monoamines, which are crucial for the physiology of neurons, synapses and neural networks. Prominent neurochemical agents of the nervous system are the monoamines dopamine and serotonin. They are commonly associated with well-being and happiness but this perception is misleading since both molecules execute very complex and diverse physiological functions in the nervous system and in other tissues (Berger at al., 2009; Meiser et al., 2013).