中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (3): 496-497.doi: 10.4103/1673-5374.293138

• 观点:退行性病与再生 • 上一篇    下一篇

神经发生与神经退行性变:阿尔茨海默病的平衡失衡

  

  • 出版日期:2021-03-15 发布日期:2020-12-17

Neurogenesis versus neurodegeneration: the broken balance in Alzheimer’s disease

Baruh Polis*, Abraham O. Samson   

  1. Drug Discovery Laboratory, The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
  • Online:2021-03-15 Published:2020-12-17
  • Contact: Baruh Polis, MD, baruhpolis@gmail.com.

摘要: https://orcid.org/0000-0002-3496-8250 (Baruh Polis)

Abstract: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, eventually manifesting in severe cognitive dysfunction. Despite the recent proliferation of encouraging preclinical studies and clinical trials, scientific society is still far from a complete consensus regarding the AD etiology and pathogenesis. Accordingly, no approved AD‐modifying therapies are currently available. Nevertheless, novel concepts predicated upon the latest discoveries and comprehension of the disease as a multifactorial disorder are paving the road to the successful AD treatment.