中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (4): 688-689.doi: 10.4103/1673-5374.295329

• 观点:退行性病与再生 • 上一篇    下一篇

代谢综合征对神经退行性疾病演变的影响

  

  • 出版日期:2021-04-15 发布日期:2020-12-21

Impact of the metabolic syndrome on the evolution of neurodegenerative diseases

Ana Paula de A. Boleti, Jeeser Alves Almeida, Ludovico Migliolo*   

  1. S-InovaBiotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, MS, Brazil (de A. Boleti AP, Migliolo L)
    Programa de Pós-Graduação em Ciências do Movimento, Programa de Pós-Graduação em Saúde e Desenvolvimento na Região Centro Oeste, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil (Almeida JA)
    Programa de Pós-graduação em Biologia Celular e Molecular, Programa de Pós-graduação em Bioquímica, Universidade Federal do Rio Grande do Norte, Natal, Brazil (Migliolo L)
  • Online:2021-04-15 Published:2020-12-21
  • Contact: Ludovico Migliolo, ludovico@ucdb.br.

摘要: https://orcid.org/0000-0002-6606-2189 (Ludovico Migliolo) 

Abstract: Metabolic syndrome (MetS) might be defined as the simultaneous accumulation of several functional changes that frequently occur in adults over 60 years of age (Gomez et al., 2018). The diagnosis of MetS requires the presence of three or more factors such as high body mass, type-2 diabetes mellitus (T2DM), dyslipidemia, and arterial hypertension, which increase the risk of cardiovascular diseases as well as neurological complications, as stroke and dementia (Dyken and Lacoste, 2018). Usually, these functional changes coincide and result in insensitivity for example hormones as leptin, adiponectin, and insulin (Dyken and Lacoste, 2018).