中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (7): 1351-1352.doi: 10.4103/1673-5374.301036

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延髓梗死患者因内侧丘系损伤致脑卒中后疼痛

  

  • 出版日期:2021-07-15 发布日期:2021-01-07

Central post-stroke pain due to injury of the medial lemniscus in a patient with medullary infarction

Sung Ho Jang, Hyeok Gyu Kwon*    

  1. Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, Republic of Korea (Jang SH)
    Department of Physical Therapy, College of Health Science, Eulji University, Seongnam, Republic of Korea (Kwon HG)
  • Online:2021-07-15 Published:2021-01-07
  • Contact: Hyeok Gyu Kwon, PhD, khg0715@hanmail.net.

摘要: https://orcid.org/0000-0002-6654-302X 
(Hyeok Gyu Kwon)

Abstract: Central post-stroke pain (CPSP), which is neuropathic pain associated with a brain lesion following a stroke, was first described by Dejerine and Roussy in 1906 in a thalamic infarct patient (Dejerine and Roussy, 1906; Watson and Sandroni, 2016). Since then, many studies have suggested that the pathophysiological mechanism underlying CPSP is activated by injury to the somatosensory nervous system (Watson and Sandroni, 2016). There are two major pathways within the somatosensory nervous system: the spinothalamic tract (STT), which is chiefly responsible for pain and touch sensations, and the medial lemniscus (ML) pathway, which is mainly involved in proprioception and tactile discrimination (Naidich et al., 2009). Many studies have suggested that STT injury is a major pathogenetic mechanism of CPSP, but a few studies have suggested that ML injury is related to the development of CPSP (Kim and Choi-Kwon, 1999; Seghier et al., 2005; Kim, 2007; Hong et al., 2010; Jang et al., 2017).