中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (9): 1871-1876.doi: 10.4103/1673-5374.303043

• 原著:视神经损伤修复保护与再生 • 上一篇    下一篇

绒猴第二视区神经元的视觉反应特征

  

  • 出版日期:2021-09-15 发布日期:2021-02-05
  • 基金资助:

    莫纳什大学和四川大学飞行项目,澳大利亚研究委员会研究项目(DP0451206),澳大利亚国家卫生与医学研究委员会项目(384115

Visual response characteristics of neurons in the second visual area of marmosets

Yin Yang1, 2, #, Ke Chen3, #, Marcello G. P. Rosa4, Hsin-Hao Yu4, Li-Rong Kuang5, Jie Yang2, 6, * #br#   

  1. 1Department of Ophthalmology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan Province, China; 2College of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, China; 3School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, China; 4Department of Physiology, Monash University, Melbourne, VIC, Australia; 5Chengdu Medical College, Chengdu, Sichuan Province, China; 6Department of Neurology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan Province, China.
  • Online:2021-09-15 Published:2021-02-05
  • Contact: Jie Yang, MS, yjsh303303@126.com.
  • Supported by:
    his study was supported by travel grants from Monash University and the University of Sichuan (to YY), and Research Grants from the Australian Research Council (No. DP0451206) (to mgpr) and National Health and Medical Research Council (No. 384115) (to MGPR).

摘要:

与初级视区(V1)相比,对绒猴第二视区(V2)生理特征的了解仍然有限。此次实验以4只成年绒猴为研究对象,通过在V2区插入钨微电极观察V2区神经元的生理反应特性。结果在绒猴V2区记录到110个神经细胞,其感受野偏心度在8°-15°间。其中大多数神经细胞(88.2%)具有方位选择性,半带宽为10°-30°。相当一部分(28.2%)具有方向选择性细胞的方向指数大于0.5。绝大多数位于V2区的神经细胞具有互不相关的空间频率和时间频率曲线,即不具速度选择性的。结果说明V2区神经细胞的电生理反应特征与V1区相似,V2区与V1区共同在灵长类动物的视觉形成中,尤其是在定位空间物体和探测物体的运动方向等方面发挥重要作用。实验已于2019年获得莫纳什大学动物伦理委员会批准,批准号MARP 2009-2011。

https://orcid.org/0000-0002-6833-2680 (Jie Yang)

关键词:

第二视区, 绒猴, 电生理特征, 方向选择性, 速度选择性, 空间频率, 时间频率, 感受野

Abstract: The physiological characteristics of the marmoset second visual area (V2) are poorly understood compared with those of the primary visual area (V1). In this study, we observed the physiological response characteristics of V2 neurons in four healthy adult marmosets using intracortical tungsten microelectrodes. We recorded 110 neurons in area V2, with receptive fields located between 8° and 15° eccentricity. Most (88.2%) of these neurons were orientation selective, with half-bandwidths typically ranging between 10° and 30°. A significant proportion of neurons (28.2%) with direction selectivity had a direction index greater than 0.5. The vast majority of V2 neurons had separable spatial frequency and temporal frequency curves and, according to this criterion, they were not speed selective. The basic functional response characteristics of neurons in area V2 resemble those found in area V1. Our findings show that area V2 together with V1 are important in primate visual processing, especially in locating objects in space and in detecting an object’s direction of motion. The methods used in this study were approved by the Monash University Animal Ethics Committee, Australia (MARP 2009-2011) in 2009. 

Key words: direction selectivity, electrophysiological recording, marmoset, orientation selectivity, receptive field, second visual area, spatial frequency, speed selectivity, temporal frequency