中国神经再生研究(英文版) ›› 2023, Vol. 18 ›› Issue (10): 2186-2187.doi: 10.4103/1673-5374.369105

• 观点:神经损伤修复保护与再生 • 上一篇    下一篇

ARNO 被神经元适配器 FE65 招募以增强 ARF6 介导的神经突生长

  

  • 出版日期:2023-10-15 发布日期:2023-03-28

Regulation of cytohesins by their interactors in the nervous system

Yuqi Zhai, King To Leung, Kwok-Fai Lau*   

  1. School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
  • Online:2023-10-15 Published:2023-03-28
  • Contact: Kwok-Fai Lau, PhD, kflau@cuhk.edu.hk.
  • Supported by:
    This work was supported by funds from Research Grants Council Hong Kong, Health and Medical Research Fund (Hong Kong), CUHK direct grant scheme, United College endowment fund and the TUYF Charitable Trust (to KFL).

摘要: https://orcid.org/0000-0002-0193-1152 (Kwok-Fai Lau)

Abstract: Adenosine diphosphate ribosylation factors (ARFs) are small GTP-binding proteins of the Ras superfamily which are involved in membrane trafficking and actin cytoskeleton remodeling. Like other small GTPases, their functions are attributed to the cycling of ARF between GTP (active) and GDP (inactive) states through the actions of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins, respectively. Cytohesins are a GEF subfamily of ARFs in mammals with four members, namely, cytohesin-1, -2, -3, and -4.