中国神经再生研究(英文版) ›› 2024, Vol. 19 ›› Issue (4): 705-706.doi: 10.4103/1673-5374.382241

• 观点:周围神经损伤修复保护与再生 • 上一篇    下一篇

坐骨神经再生的新免疫调节因子?从邻居那里得到的教训

  

  • 出版日期:2024-04-15 发布日期:2023-09-15

New immune regulators of sciatic nerve regeneration? Lessons from the neighborhood

André L. Bombeiro*, Rodrigo G.Q. Fernandes, Julie C. Ribot*#br#   

  1. Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
  • Online:2024-04-15 Published:2023-09-15
  • Contact: Julie C. Ribot, PhD, jribot@medicina.ulisboa.pt; André L. Bombeiro, PhD, andre.bombeiro@medicina.ulisboa.pt.
  • Supported by:
    This work was funded by the Fundacao para a Ciencia e Tecnologia (2020.00413.CEECIND and 2022.01244.PTDC, to JCR).

摘要: https://orcid.org/0000-0002-7852-343X (Julie C. Ribot)
https://orcid.org/0000-0003-2303-8127 (André L. Bombeiro)

Abstract: For decades, the immune system has been associated with host protection against infectious pathogens or tumors, while also contributing to autoimmunity. Notwithstanding, this paradigm is now changing, with recent studies highlighting novel roles for immune mediators in the maintenance of steady-state tissue homeostasis. In this perspective, we review some of the latest findings featuring immune modulators of the nervous system pathophysiology, with a special focus on interleukin (IL)-17.