中国神经再生研究(英文版) ›› 2024, Vol. 19 ›› Issue (7): 1435-1436.doi: 10.4103/1673-5374.386402

• 观点:神经损伤修复保护与再生 • 上一篇    下一篇

线粒体建模:数量在哪里? 

  

  • 出版日期:2024-07-15 发布日期:2023-11-28

Modeling mitochondria, where are the numbers?

Adrian M. Davies*, Alan G. Holt*   

  1. University Center Shrewsbury, Shrewsbury, Shropshire, UK
  • Online:2024-07-15 Published:2023-11-28
  • Contact: Adrian M. Davies, PhD, arian.m.davies@gmail.com; Alan G. Holt, PhD, agholt@gmail.com.

摘要: https://orcid.org/0000-0002-1073-3211 (Adrian M. Davies)

Abstract: Models and simulations are particularly useful for exploring ideas and concepts in the biological sciences that are experimentally impracticable.
In silico methods are also gaining acceptance with regulatory authorities as an alternative to animal testing. For example, the Environmental Protection Agency aims to eliminate animal testing by 2035, and both the Food and Drug Administration and European Medicine Agency no longer require animal testing for biosimilars or generic products if the in vitro and in silico data is acceptable.