中国神经再生研究(英文版) ›› 2024, Vol. 19 ›› Issue (7): 1429-1430.doi: 10.4103/1673-5374.387992

• 观点:周围神经损伤修复保护与再生 • 上一篇    下一篇

垂体腺苷酸环化酶激活多肽与周围神经再生:细胞和分子视角观察的作用机制

  

  • 出版日期:2024-07-15 发布日期:2023-11-28

Role of pituitary adenylate cyclase-activating polypeptide in peripheral nerve regeneration: a cellular and molecular perspective

Grazia Maugeri, Velia D’Agata*   

  1. Section of Anatomy, Histology and Movement Sciences, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy
  • Online:2024-07-15 Published:2023-11-28
  • Contact: Velia D’Agata, PhD, vdagata@unict.it.
  • Supported by:
    This work was supported by PIAno di inCEntivi per la RIcerca di Ateneo 2020/2022 Linea di Intervento 3 “Starting Grant” “REPAIR” (to GM).

摘要: https://orcid.org/0000-0003-1114-8265 (Velia D’Agata)

Abstract: Neuroregeneration is a very complex phenomenon characterized by the generation of new neurons and synapses, involving connections between adjacent cells and axonal projections. Neuroregeneration supplies additional long-term resources to replace those altered by the injury and ensure lasting functional recovery. There are substantial differences between the neurodegeneration in the peripheral nervous system (PNS) and the central nervous system (CNS) particularly in terms of extent and speed. In fact, the PNS has remarkable regenerative properties, both morphological and functional, whereas the CNS is most unable to self-repair and regenerate.