中国神经再生研究(英文版) ›› 2026, Vol. 21 ›› Issue (3): 1138-1139.doi: 10.4103/NRR.NRR-D-24-01289

• 观点:脊髓损伤修复保护与再生 • 上一篇    下一篇

脊髓网状结构在脊髓损伤后运动控制和功能恢复中的作用

  

  • 出版日期:2026-03-15 发布日期:2025-07-04

Role of the medullary reticular formation in motor control and functional recovery following spinal cord injury

Frederic Bretzner*   

  1. Centre de Recherche du CHU de Québec, CHULNeurosciences, Québec, QC, Canada Faculty of Medicine, Department of Psychiatry and Neuroscience, Université Laval, Québec, QC, Canada
  • Online:2026-03-15 Published:2025-07-04
  • Contact: Frederic Bretzner, PhD, frederic.bretzner.1@ulaval.ca.
  • Supported by:
    This work was supported by Craig H. Neilsen Foundation, Wings for Life Foundation, Canadian Institutes of Health Research, and Fonds de Recherche Québec-Santé (to FB).

摘要: https://orcid.org/0000-0002-7387-3414 (Frederic Bretzner)

Abstract: Spinal cord injury (SCI) interrupts the flow of information between the brain and the spinal cord, thus leading to a loss of sensory information and motor paralysis of the body below the lesion. Surprisingly, most SCIs are incomplete and spare supraspinal pathways, especially those located within the peripheral white matter of the spinal cord, which includes reticulospinal pathways originating from the medullary reticular formation. Whereas there is abundant literature about the motor cortex, its corticospinal pathway, and its capacity to modulate functional recovery after SCI, less is known about the medullary reticular formation and its reticulospinal pathway.