中国神经再生研究(英文版) ›› 2026, Vol. 21 ›› Issue (10): 4914-4915.doi: 10.4103/NRR.NRR-D-25-01728

• 观点:退行性病与再生 • 上一篇    下一篇

脑-免疫轴的数字神经可塑性调节:神经退行性病和精神病及衰老相关疾病的翻译策略

  

  • 出版日期:2026-10-15 发布日期:2026-06-13

Digital neuroplasticity modulation of the brain-immune axis: Translational strategies for neurodegenerative, psychiatric, and aging-related conditions

Merav Catalogna, Amir Amedi*   

  1. Dina Recanati School of Medicine, Reichman University, Herzliya, Israel (Catalogna M, Amedi A) 
    Baruch Ivcher Institute for Brain, Cognition, and Technology, Baruch Ivcher School of Psychology, Reichman University, Herzliya, Israel (Catalogna M, Amedi A)
  • Online:2026-10-15 Published:2026-06-13
  • Contact: Amir Amedi, PhD, amir.amedi@runi.ac.il.

摘要: https://orcid.org/0000-0001-5042-2533 (Amir Amedi)

Abstract: The brain–immune axis: The dynamic interplay between neural and immune systems is emerging as a fundamental regulator of cognitive processes, affective balance, and resilience to pathological challenges (Castellani et al., 2023). Although these systems detect and respond to distinct types of stimuli, their domains of perception and response substantially overlap. The nervous system primarily encodes physical and sensory stimuli, such as light, sound, temperature, and mechanical pressure, while the immune system detects molecular cues, including pathogens, cytokines, and endogenous danger signals. Together, both systems integrate biochemical, circadian, metabolic, and stress-related inputs to maintain adaptive and coordinated responses to internal and external perturbations (Leunig et al., 2025).