中国神经再生研究(英文版) ›› 2019, Vol. 14 ›› Issue (1): 72-74.

• 观点:退行性病与再生 • 上一篇    下一篇

血液外泌体作为监测神经退行性疾病的治疗功效和进展的工具

  

  • 出版日期:2019-01-15 发布日期:2019-01-15

Blood exosomes as a tool for monitoring treatment efficacy and progression of neurodegenerative diseases

Hanin Abdel-Haq   

  1. National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy
  • Online:2019-01-15 Published:2019-01-15
  • Contact: Hanin Abdel-Haq, PhD, hanin.abdelhaq@iss.it.

摘要:

orcid: 0000-0001-5486-3037 (Hanin Abdel-Haq)

Abstract:

Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, and prion disease are representative neurodegenerative diseases that share common sub-cellular features, the most obvious of which is a strong association with the accumulation of misfolded, aggregated, and insoluble forms of proteins in the brain, as evidenced in post-mortem brain tissues of patients.