中国神经再生研究(英文版) ›› 2023, Vol. 18 ›› Issue (6): 1257-1258.doi: 10.4103/1673-5374.360167

• 观点:脑损伤修复保护与再生 • 上一篇    下一篇

小鼠创伤性脑损伤后成年对侧皮层胼胝体神经元的选择性可塑性

  

  1. 慕尼黑生物医学中心,慕尼黑大学医学院,德国
  • 出版日期:2023-06-15 发布日期:2022-12-22

Plasticity of callosal neurons in the contralesional cortex following traumatic brain injury

Alexandra Chovsepian, Laura Empl, Florence M. Bareyre   

  1. Institute of Clinical Neuroimmunology, Biomedical Building and Clinic of the Ludwig-Maximilians Universität München, Munich, Germany (Chovsepian A, Empl L, Bareyre FM) 
    Munich Cluster of Systems Neurology (SyNergy), Munich, Germany (Bareyre FM) 
  • Online:2023-06-15 Published:2022-12-22
  • Contact: Florence M. Bareyre, PhD, florence.bareyre@med.uni-muenchen.de.
  • Supported by:
    Work in FMB’s lab is supported by grants from the Deutsche Forschungsgemeinschaft (DFG, TRR274/1, ID 408885537, Project C03), the Wings for Life and the Humboldt foundation. FMB is also supported by the Munich Center for Systems Neurology (DFG, SyNergy; EXC 2145/ID 390857198). 

摘要: https://orcid.org/0000-0002-0917-1725 (Florence M. Bareyre) 

Abstract: Traumatic brain injury (TBI) represents a significant cause of disability worldwide. It creates a vast array of damaging macro- and microscopic changes in the affected brain area(s), ranging from neuronal cell death, changes in structural spine integrity and dynamics to axonal injury and overall neuronal circuit disruption, ultimately leading to functional and cognitive deficits in both humans and animal models (Nudo, 2013).