中国神经再生研究(英文版) ›› 2012, Vol. 7 ›› Issue (21): 1637-1644.

• 综述:神经损伤修复保护与再生 • 上一篇    下一篇

Curve interpolation model for visualising disjointed neural elements

  

  • 收稿日期:2012-04-15 修回日期:2012-05-14 出版日期:2012-07-25 发布日期:2012-07-25

Curve interpolation model for visualising disjointed neural elements

Mohd Shafry Mohd Rahim1, Norhasana Razzali1, Mohd Shahrizal Sunar1, Ayman Abdualaziz Abdullah2, Amjad Rehman2   

  1. 1 UTMViCubeLab, Department of Computer Graphics and Multimedia, FSKSM, University of Technology, Skudai 81310, Malaysia
    2 College of Applied Studies and Community Service, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia
  • Received:2012-04-15 Revised:2012-05-14 Online:2012-07-25 Published:2012-07-25
  • Contact: Amjad Rehman, Ph.D. Assistant professor, College of Applied Studies, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia rkamjad@gmail.com
  • About author:Mohd Shafry Mohd Rahim☆, Ph.D. Assistant professor, UTMViCubeLab, Department of Computer Graphics and Multimedia, FSKSM, University Technology Malaysia, Malaysia

Abstract:

Neuron cell are built from a myriad of axon and dendrite structures. It transmits electrochemical signals between the brain and the nervous system. Three-dimensional visualization of neuron structure could help to facilitate deeper understanding of neuron and its models. An accurate neuron model could aid understanding of brain’s functionalities, diagnosis and knowledge of entire nervous system. Existing neuron models have been found to be defective in the aspect of realism. Whereas in the actual biological neuron, there is continuous growth as the soma extending to the axon and the dendrite; but, the current neuron visualization models present it as disjointed segments that has greatly mediated effective realism. In this research, a new reconstruction model comprising of the Bounding Cylinder, Curve Interpolation and Gouraud Shading is proposed to visualize neuron model in order to improve realism. The reconstructed model is used to design algorithms for generating neuron branching from neuron SWC data. The Bounding Cylinder and Curve Interpolation methods are used to improve the connected segments of the neuron model using a series of cascaded cylinders along the neuron’s connection path. Three control points are proposed between two adjacent neuron segments. Finally, the model is rendered with Gouraud Shading for smoothening of the model surface. This produce a near-perfection model of the natural neurons with attended realism. The model is validated by a group of bioinformatics analysts’ responses to a predefined survey. The result shows about 82% acceptance and satisfaction rate.

Key words: bounding cylinder, curve interpolation, reconstruction model, Gouraud shading, neural regeneration