中国神经再生研究(英文版) ›› 2022, Vol. 17 ›› Issue (12): 2697-2699.doi: 10.4103/1673-5374.339485

• 观点:视神经损伤修复保护与再生 • 上一篇    下一篇

寻找“田园诗般的”动物模型评估眼部病变并转化新疗法以改善人类健康

  

  • 出版日期:2022-12-15 发布日期:2022-05-05

In search for the “idyllic” animal model to evaluate ocular pathologies and translate new therapies to improve human health

Francisco M. Nadal-Nicolás*, Kiyoharu J. Miyagishima, Wei Li   

  1. Retinal Neurophysiology Section, National Eye Institute, National Institutes of Health, Bethesda, MD, USA
  • Online:2022-12-15 Published:2022-05-05
  • Contact: Francisco M. Nadal-Nicolás, PhD, nadalnicolasfm@nih.gov.

摘要: https://orcid.org/0000-0003-4121-514X (Francisco M. Nadal-Nicolás)
https://orcid.org/0000-0002-9744-3152 (Kiyoharu J. Miyagishima) 
https://orcid.org/0000-0002-2897-649X (Wei Li) 

Abstract: The retina is a highly specialized neural tissue that encodes information of vision, a vital sensory modality for most species. Although the retina also contributes to other non‐image‐forming signals (e.g. entrainment of circadian clocks), vision chiefly enables animals to interpret and navigate their environment (despite the diverse variety of species and lifestyles; Baden et al., 2020) and also to interact with other animals. Thus, features such as high visual resolution and color discrimination are important for interactive behaviors like prey capture and also for social animals, including primates, that establish a dominance hierarchy.