中国神经再生研究(英文版) ›› 2014, Vol. 9 ›› Issue (3): 234-235.doi: 10.4103/1673-5374.128211

• 观点:颅神经损伤修复保护与再生 • 上一篇    下一篇

核磁共振成像即时评价短暂性脑缺血发挥神经保护作用

  

  • 收稿日期:2014-01-29 出版日期:2014-02-15 发布日期:2014-02-15

Magnetic resonance imaging in patients with transient ischemic attack

Mohamed Al-Khaled   

  1. Department of Neurology, University of Lübeck, 23538 Lübeck, Germany
  • Received:2014-01-29 Online:2014-02-15 Published:2014-02-15
  • Contact: Mohamed Al-Khaled, M.D., Department of Neurology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany, Mohamed.al-khaled@neuro.uni-luebeck.de.

摘要:

短暂性脑缺血发作(TIA)属于瞬时性事件,预示着TIA后罹患致残性脑卒中的危险性升高。然而,在世界范围,研究人员对TIA的评估和管理体系各持己见,并且仍然存在较大争议。德国吕贝克大学Mohamed Al-Khaled博士认为,脑部成像,特别是DWI-MRI的发展,使得TIA的诊断从基于时间定义改变为基于组织判断,DWI-MRI已成为TIA后处理的必须手段。DWI-MRI不仅能够提供区分TIA和急性缺血性卒中的证据,还能够预测哪些TIA患者更容易罹患致残性脑卒中,并且能以即时评估神经元的状态指导治疗,预防病变加重,产生好的神经保护效应。

Abstract:

Transient ischemic attack (TIA) is a temporary event, which portends a higher risk of a disabling stroke following the TIA. However, the evaluation and management of TIA vary worldwide and is debated and controversial. Dr. Mohamed Al-Khaled from University of Lübeck in Germany considered With the development of brain imaging, particularly diffusion weighted imaging-magnetic resonance imaging (DWI-MRI), the diagnosis of TIA changed from time-based definition to a tissue-based one. DWI-MRI became a mandatory tool in the TIA workup. The DWI-MRI provides not only the evidence to distinguish between TIA and acute ischemic stroke, furthermore it predicts TIA patients who are at higher risk of disabling stroke, which can be prevented by an immediate evaluation and treatment of TIA These findings, published in the Neural Regeneration Research (Vol. 9, No. 3, 2014).