中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2013, Vol. 8 ›› Issue (11): 1048-1054.doi: 10.3969/j.issn.1673-5374.2013.11.011

• 原著:神经损伤修复保护与再生 • 上一篇    

提高患者运动控制能力：经颅直流电刺激能实现吗？

  

  • 收稿日期:2012-11-06 修回日期:2013-03-06 出版日期:2013-04-15 发布日期:2013-04-15

Is transcranial direct current stimulation a potential method for improving response inhibition?

Yong Hyun Kwon1, Jung Won Kwon2   

  1. 1 Department of Physical Therapy, Yeungnam College of Science & Technology, Daegu 705-703, Republic of Korea
    2 Department of Physical Therapy, College of Rehabilitation Science, Daegu University, Gyeongbuk 712-714, Republic of Korea
  • Received:2012-11-06 Revised:2013-03-06 Online:2013-04-15 Published:2013-04-15
  • Contact: Jung Won Kwon, M.S., P.T., Department of Rehabilitation Science, Graduate School, Daegu University, 15, Jilyang, Gyeongsan-si, Kyeongbuk, 712-714, Republic of Korea, kjwonpt@gmail.com
  • About author:Yong Hyun Kwon☆, Ph.D., P.T.
  • Supported by:

    韩国教育、科学技术部基础研究基金(No. 2012R1A1B4003477)

PDF

797

摘要：

为研究经颅直流电刺激脑前辅助运动区对停止信号任务中运动抑制的反应时的影响，纳入40例健康受试者，给予其经颅直流电刺激脑前辅助运动区或假电刺激。受试在未给予电刺激、电刺激期间、电刺激后3个连续阶段执行停止信号任务。发现电刺激期间和电刺激后，停止信号任务的反应时明显缩短。结果提示颅直流电刺激和停止信号任务给予大脑的刺激可改善运动控制能力障碍。

关键词: 神经再生, 经康复, 颅直流电刺激, 辅助运动区, 止信号任务, 应抑制, 制控制, 动学习, 为修正, 金资助文章

Abstract:

Inhibitory control of movement in motor learning requires the ability to suppress an inappropriate action, a skill needed to stop a planned or ongoing motor response in response to changes in a variety of environments. This study used a stop-signal task to determine whether transcranial direct-current stimulation over the pre-supplementary motor area alters the reaction time in motor inhibition. Forty healthy subjects were recruited for this study and were randomly assigned to either the transcranial direct-current stimulation condition or a sham-transcranial direct-current stimulation condition. All subjects consecutively performed the stop-signal task before, during, and after the delivery of anodal transcranial direct-current stimulation over the pre-supplementary motor area (pre-transcranial direct-current stimulation phase, transcranial direct-current stimulation phase, and post-transcranial direct-current stimulation phase). Compared to the sham condition, there were significant reductions in the stop-signal processing times during and after transcranial direct-current stimulation, and change times were significantly greater in the transcranial direct-current stimulation condition. There was no significant change in go processing-times during or after transcranial direct-current stimulation in either condition. Anodal transcranial direct-current stimulation was feasibly coupled to an interactive improvement in inhibitory control. This coupling led to a decrease in the stop-signal process time required for the appropriate responses between motor execution and inhibition. However, there was no transcranial direct-current stimulation effect on the no-signal reaction time during the stop-signal task. Transcranial direct-current stimulation can adjust certain behaviors, and it could be a useful clinical intervention for patients who have difficulties with response inhibition.

Key words: neural regeneration, eurorehabilitation, ranscranial direct current stimulation, re-supplementary motor area, top-signal task, esponse inhibition, inhibitory control, otor learning, ehavioral modification, rants-supported paper, neuroregeneration