中国神经再生研究(英文版) ›› 2016, Vol. 11 ›› Issue (1): 126-129.doi: 10.4103/1673-5374.175057

• 原著:脑损伤修复保护与再生 • 上一篇    下一篇

大脑半球偏侧化影响经颅直流电刺激效应?

  

  • 出版日期:2016-01-15 发布日期:2016-01-15

Does hemispheric lateralization influence therapeutic effects of transcranial direct current stimulation?

Yong Hyun Kwon 1, Kyung Woo Kang 2, Na Kyung Lee 2, Sung Min Son 3   

  1. 1 Department of Physical Therapy, Yeungnam University College, Daemyung-dong, Namgu, Daegu, Republic of Korea
    2 Department of Physical Therapy, College of Rehabilitation Science, Daegu University, Jilyang, Gyeongsan-si, Kyeongbuk, Republic of Korea
    3 Department of Physical Therapy, College of Health Science, Cheongju University, Daeseong-ro, Cheongju-si, Chungbuk, Republic of Korea
  • Online:2016-01-15 Published:2016-01-15
  • Contact: Kyung Woo Kang, M.S.,zephyr0001@hanmail.net.

摘要:

为研究经颅直流电刺激对正常人执行视觉运动和简单重复任务时是否存在大脑半球偏侧化,试验纳入30名健康受试者,其分别在给予强度2mA的经颅直流电刺激右侧大脑半球15min或只是将电极置于相同位置的假刺激,而不刺激30s。在两种条件前后均执行敲打和追踪任务,即简单重复任务和视觉运动协调任务。单变量分析显示,只有追踪任务在经颅直流电刺激与不刺激的情况下存在差异。经颅直流电刺激右侧大脑半球的受试者在执行追踪任务时比执行敲打任务时的Z分更高。说明经颅直流电刺激右侧大脑半球可有效改善视觉运动任务,而对简单重复任务无明显作用。

关键词: 经颅直流电刺激, 视觉运动任务, 追踪任务, 任务特性, 大脑半球偏侧化

Abstract:

This study investigated the effect of transcranial direct current stimulation (tDCS) polarity depending on lateralized function of task property in normal individuals performing visuomotor and simple repetitive tasks. Thirty healthy participants with no neurological disorders were recruited to participate in this study. Participantswere randomly allocated into active or control condition. For the active condition, tDCS intensity was 2 mA with stimulation applied for 15 minutes to the right hemisphere (tDCS condition). For the sham control, electrodes were placed in the same position, but the stimulator was turned off after 30 seconds (sham condition).The tapping and tracking task tests were performed before and after for both conditions. Univariate analysis revealed significant difference only in the tracking task. For direct comparison of both tasks within each group, the tracking task had significantly higher Z score than the tapping task in the tDCS group (P < 0.05). Thus, our study indicates that stimulation of the right hemisphere using tDCS can effectively improve visuomotor (tracking) task over simple repetitive (tapping) task.

Key words: nerve regeneration, transcranial direct current stimulation, visuomotor task, tracking task, task property, hemispheric lateralization, neural regeneration