中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2015, Vol. 10 ›› Issue (3): 463-466.doi: 10.4103/1673-5374.153697

• 原著:视神经损伤修复保护与再生 • 上一篇    下一篇

经颅直流电刺激对视觉运动协调能力的影响依赖于视觉运动追踪任务难度？

  

  • 收稿日期:2015-02-11 出版日期:2015-03-20 发布日期:2015-03-20
  • 基金资助:

    韩国教育科技部基础科学研究项目(2012R1A1B4003477)

Is effect of transcranial direct current stimulation on visuomotor coordination dependent on task difficulty?

Yong Hyun Kwon 1, Kyung Woo Kang 2, Sung Min Son 3, Na Kyung Lee 2   

  1. 1 Department of Physical Therapy, Yeungnam University College,170, Daemyung-dong, Namgu, Daegu, 705-703, Republic of Korea
    2 Department of Physical Therapy, College of Rehabilitation Science, Daegu University, 15, Jilyang, Gyeongsan-si, Kyeongbuk, 712-714, Republic of Korea
    3 Department of Physical Therapy, College of Health Science, Cheongju University, 298 Daeseong-ro, Cheongwon-gu, Cheongju-si, Chungbuk 363-764, Republic of Korea
  • Received:2015-02-11 Online:2015-03-20 Published:2015-03-20
  • Contact: Na Kyung Lee, Ph.D., dlskrud21@hanmail.net
  • Supported by:

    This work was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning, No. 2012R1A1B4003477.

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摘要：

研究的目的在于探讨经颅直流电刺激初级运动皮质对视觉运动协调能力的影响。随机将38名健康者分为电刺激组和假刺激组。采用单盲，假手术对照交叉设计，颅直流电刺激强度1 mA，持续15min。假刺激组只放置电极，但不给予电刺激。参与者分别于电刺激前后执行包括3个难度水平的视觉运动追踪任务。水平2任务的执行使经颅电刺激初级运动皮质可改善反映视觉运动协调能力的精确指数。但在执行难度为水平1和3的任务不能使精确指数明显改善。结果表明，中等难度的任务可以提高经颅电刺激对视觉运动协调功能的改善作用。

关键词: 神经再生, 电刺激, 经颅直流电刺激, 运动皮质, 大脑皮质, 视觉运动协调

Abstract:

Transcranial direct current stimulation (tDCS), an emerging technique for non-invasive brain stimulation, is increasingly used to induce changes in cortical excitability and modulate motor behavior, especially for upper limbs. The purpose of this study was to investigate the effects of tDCS of the primary motor cortex on visuomotor coordination based on three levels of task difficulty in healthy subjects. Thirty-eight healthy participants underwent real tDCS or sham tDCS. Using a single-blind, sham-controlled crossover design, tDCS was applied to the primary motor cortex. For real tDCS conditions, tDCS intensity was 1 mA while stimulation was applied for 15 minutes. For the sham tDCS, electrodes were placed in the same position, but the stimulator was turned off after 5 seconds. Visuomotor tracking task, consisting of three levels (levels 1, 2, 3) of difficulty with higher level indicating greater difficulty, was performed before and after tDCS application. At level 2, real tDCS of the primary motor cortex improved the accurate index compared to the sham tDCS. However, at levels 1 and 3, the accurate index was not significantly increased after real tDCS compared to the sham tDCS. These findings suggest that tasks of moderate difficulty may improve visuomotor coordination in healthy subjects when tDCS is applied compared with easier or more difficult tasks.

Key words: neural regeneration, transcranial direct current stimulation, visuomotor coordination, task difficulty, primary motor area, motor learning, neural regeneration