中国神经再生研究(英文版) ›› 2017, Vol. 12 ›› Issue (10): 1742-1744.doi: 10.4103/1673-5374.217355

• 综述:脑损伤修复保护与再生 • 上一篇    

弥散张量纤维束成像揭示损伤穹窿恢复机制

  

  • 收稿日期:2017-05-10 出版日期:2017-10-15 发布日期:2017-10-15
  • 基金资助:

    韩国政府国家研究基金

Diffusion tensor tractography studies on mechanisms of recovery of injured fornix

Sung Ho Jang, Han Do Lee   

  1. Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Daegu, Republic of Korea
  • Received:2017-05-10 Online:2017-10-15 Published:2017-10-15
  • Contact: Han Do Lee,lhd890221@hanmail.net.
  • Supported by:

    This work was supported by the National Research Foundation (NRF) of Korea Grant funded by the Korean Government (MSIP)(2015R1A2A2A01004073).

摘要:

  目前共有5项研究应用弥散张量纤维束成像揭示了损伤穹窿的恢复机制:(1)经正常穹窿脚通路,从穹窿脚至损伤内侧颞叶神经束的恢复。(2)经胼胝体压部,通过起始于与损伤侧内侧颞叶连接的穹窿体的神经束的恢复。(3)经胼胝体压部,通过损伤侧穹窿体延伸至对侧内侧颞叶的神经束的恢复。(4)起始于与损伤侧内侧颞叶连接的损伤侧穹窿柱的神经束的恢复。(5)经对侧内侧颞叶和胼胝体压部,起始于与损伤侧内侧颞叶连接的对侧穹窿柱的神经束的恢复。这些弥散张量纤维束成像可为临床有针对性地治疗穹窿损伤患者提供有用信息。

orcid:0000-0002-1668-2187(Han Do Lee)

 

关键词: 神经再生, 穹窿, 弥散张量纤维束成像, 恢复机制, 神经束, 综述

Abstract:

The fornix, which connects the medial temporal lobe and the medial diencephalon, is involved in episodic memory as an important part of the Papez circuit. The mechanisms of recovery of an injured fornix revealed by diffusion tensor tractography in the five studies are summarized as follows: 1) recovery through the nerve tract from an injured fornical crus to the medial temporal lobe via the normal pathway of the fornical crus; 2) recovery through the nerve tract originating from an ipsi-lesional fornical body connected to the ipsi-lesional medial temporal lobe via the splenium of the corpus callosum; 3) recovery through the nerve tract from the ipsi-lesional fornical body extending to the contra-lesional medial temporal lobe via the splenium of the corpus callosum; 4) recovery through the nerve tract originating from the ipsi-lesional fornical column connected to the ipsi-lesional medial temporal lobe; and 5) recovery through the nerve tract originating from the contra-lesional fornical column connected to the ipsi-lesional medial temporal lobe via the contra-lesional medial temporal lobe and the splenium of the corpus callosum. These diffusion tensor tractography studies on mechanisms of recovery of injured fornical crus appeared to provide useful information for clinicians caring for patients with brain injury, however, studies on this topic are still in the beginning stages.