中国神经再生研究(英文版) ›› 2023, Vol. 18 ›› Issue (6): 1265-1266.doi: 10.4103/1673-5374.358621

• 观点:退行性病与再生 • 上一篇    下一篇

Luteolin-7-O-Glucoside 对 6-OHDA 诱导的未分化和 RA 分化 SH-SY5Y 细胞损伤的神经保护作用

  

  1. 生物技术研究生课程,伊塔雅伊淡水河谷大学,巴西; 药学研究所,药物化学和蒂宾根学术药物发现中心,埃伯哈德卡尔斯大学蒂宾根分校,德国
  • 出版日期:2023-06-15 发布日期:2022-12-22

Neural regeneration research model to be explored: SH-SY5Y human neuroblastoma cells

Lavynia Ferreira Hoffmann, Alexandre Martins, Fernanda Majolo, Verônica Contini, Stefan Laufer, Márcia Inês Goettert*#br#   

  1. Graduate Program in Biotechnology, University of Vale do Taquari (Univates), Lajeado, Rio Grande do Sul, Brazil (Hoffmann LF, Martins A, Contini V, Goettert MI) 
    Graduate Program in Medical Sciences - PPGCM, University of Vale do Taquari - Univates, Lajeado/RS, Brazil (Majolo F, Contini V, Goettert MI) 
    Institute of Pharmacy, Pharmaceutical/Medicinal Chemistry and Tübingen Center for Academic Drug Discovery - TÜCADD, Eberhard Karls University Tübingen, Tübingen, Germany (Laufer S, Goettert MI) 
  • Online:2023-06-15 Published:2022-12-22
  • Contact: Márcia Inês Goettert, PhD, m.goettert@uni-tuebingen.de or stefan.laufer@uni-tuebingen.de.
  • Supported by:
    This work was supported in part by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Capes-Brazil), No. 001 (to MIG). 

摘要: https://orcid.org/0000-0002-3648-5033 (Márcia Inês Goettert) 

Abstract: In neuroscience research, neuronal models are crucial tools for elucidating the molecular and cellular processes involved in the disorders of the nervous system. Facilitating easily and reproducibly executable studies, in vitro models, such as the SH-SY5Y cell line culture, help us explore the pathophysiological mechanisms of neurodegenerative diseases; they are also essential for the efficient screening of drugs for treating the diseases of the nervous system (Peng et al., 2021; Strother et al., 2021).