中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2012, Vol. 7 ›› Issue (20): 1563-1589.

• 原著:脑损伤修复保护与再生 • 上一篇    下一篇

Preoperative functional MRI localization of language areas in Chinese patients with brain tumors

  

  • 收稿日期:2012-03-05 修回日期:2012-06-15 出版日期:2012-07-15 发布日期:2012-07-15

Preoperative functional MRI localization of language areas in Chinese patients with brain tumors

Hechun Xia1, Wei Huang2, Liang Wu1, Hui Ma1, Xiaodong Wang1, Xuexin Chen1, Shengyu Sun1, Xiaoxiong Jia1   

  1. 1  Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China
    2  Department of Neurosurgery, Hanzhong Central Hospital, Hanzhong 723000, Shaanxi Province, China
  • Received:2012-03-05 Revised:2012-06-15 Online:2012-07-15 Published:2012-07-15
  • Contact: Hechun Xia, Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China xhechun@yahoo.com.cn
  • About author:Hechun Xia, Professor, Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Auto-nomous Region, China

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关键词: functional MRI, brain tumor, Chinese language, brain mapping, intraoperative electrocortical mapping, Wernicke’s area, Broca’s area, regeneration, neural regeneration

Abstract:

Ten Chinese patients with brain tumors involving language regions were selected. Preoperative functional MRI was performed to locate Broca’s or Wernicke’s area, and the cortex that was essential for language function was determined by electrocortical mapping. A site-by-site comparison between functional MRI and electrocortical mapping was performed with the aid of a neuronavigation device. Results showed that the sensitivity and specificity of preoperative functional MRI were 80.0% and 85.0% in Broca’s area and 66.6% and 85.2% in Wernicke’s area, respectively. These experimental findings indicate that functional MRI is an accurate, reliable technique with which to identify the location of Wernicke’s area or Broca’s area in patients with brain tumors.

Key words: functional MRI, brain tumor, Chinese language, brain mapping, intraoperative electrocortical mapping, Wernicke’s area, Broca’s area, regeneration, neural regeneration