中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (9): 1803-1804.doi: 10.4103/1673-5374.306068

• 观点:神经损伤修复保护与再生 • 上一篇    下一篇

神经营养因子是神经元和牙齿所说的第二语言吗?

  

  • 出版日期:2021-09-15 发布日期:2021-02-05

Is neurotrophic factor a second language that neuron and tooth speak?

Nan Xiao*   

  1. Department of Biomedical Sciences, Arthur A. Dugoni School of Dentistry, University of the Pacific, San Francisco, CA, USA
  • Online:2021-09-15 Published:2021-02-05
  • Contact: Nan Xiao, PhD, MOrtho, DDS, nxiao@pacific.edu.

摘要: https://orcid.org/0000-0001-7264-3046
(Nan Xiao) 

Abstract: Neurotrophic factors are growth factors that can nourish neurons and promote neuron survival and regeneration. Dental origin mesenchymal stem cells express various neurotrophic factors during tooth development and the expression level changes during cell differentiation. Dental origin stem cells are reported to mediate neuronal tissue repair by increasing the secretion of neurotrophic factors. On the other hand, neurotrophic factors promote survival, proliferation, angiogenesis, migration and neuron - like differentiation in dental origin stem cells, which can be applied to the dental clinic. The prospective emphasizes the connection of the dental pulp stem cells and nervous system through neurotrophic factors.