中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2012, Vol. 7 ›› Issue (30): 2362-2369.

• 原著:脑损伤修复保护与再生 • 上一篇    下一篇

针刺“得气”时激活与负激活的脑部功能区：功能磁共振成像研究

  

  • 收稿日期:2012-05-11 修回日期:2012-07-10 出版日期:2012-10-25 发布日期:2012-10-25

Activated and deactivated functional brain areas in the Deqi state A functional MRI study

Yong Huang1, Tongjun Zeng2, Guifeng Zhang3, Ganlong Li4, Na Lu5, Xinsheng Lai6, Yangjia Lu7, Jiarong Chen8   

  1. 1 Traditional Chinese Medicine School, Southern Medical University, Guangzhou 510515, Guangdong Province, China
    2 Rehabilitation Department, First People’s Hospital, Shunde District, Foshan 528300, Guangdong Province, China
    3 Academic Affairs Department, Xinxing Chinese Medicine School, Xinxing 527400, Guangdong Province, China
    4 Traditional Chinese Medicine Department, Huarui Hospital, Southern Medical University, Guangzhou 510360, Guangdong Province, China
    5 Medicophysics Department, Guangzhou Medical University, Guangzhou 510182, Guangdong Province, China
    6 Acupuncture and Massage College, Guangzhou Traditional Chinese Medicine University, Guangzhou 510405, Guangdong Province, China
    7 Traditional Chinese Medicine Department, Guangdong Medical College, Dongguan 523808, Guangdong Province, China
    8 First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, Guangdong Province, China
  • Received:2012-05-11 Revised:2012-07-10 Online:2012-10-25 Published:2012-10-25
  • Contact: Xin-sheng Lai, M.D., Professor, Chief physician, Doctoral supervisor, Acupuncture and Massage College, Guang-zhou Traditional Chinese Medicine University, Guang-zhou 510405, Guangdong Province, China Lai1023@163.com
  • About author:Yong Huang☆, M.D., Pro-fessor, Chief physician, Doctoral supervisor, Tradi-tional Chinese Medicine School, Southern Medical University, Guangzhou 510515, Guangdong Prov-ince, China

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Abstract:

We compared the activities of functional regions of the brain in the Deqi versus non-Deqi state, as reported by physicians and subjects during acupuncture. Twelve healthy volunteers received sham and true needling at the Waiguan (TE5) acupoint. Real-time cerebral functional MRI showed that compared with non-sensation after sham needling, true needling activated Brodmann areas 3, 6, 8, 9, 10, 11, 13, 20, 21, 37, 39, 40, 43, and 47, the head of the caudate nucleus, the parahippocampal gyrus, thalamus and red nucleus. True needling also deactivated Brodmann areas 1, 2, 3, 4, 5, 6, 7, 9, 10, 18, 24, 31, 40 and 46.

Key words: needling, sham needling, Waiguan (TE5), sham point, Deqi, functional MRI, brain region activation, deactivation, neural regeneration