中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2016, Vol. 11 ›› Issue (7): 1180-1184.doi: 10.4103/1673-5374.187063

• 原著:周围神经损伤修复保护与再生 • 上一篇    下一篇

低功率激光治疗腕管综合征：有效光功率参数监测

  

  • 出版日期:2016-07-30 发布日期:2016-07-30
  • 基金资助:
    国家自然科学基金(61108077)

Low-power laser therapy for carpal tunnel syndrome: effective optical power

Yan Chen1, *, Cheng-qiang Zhao2, Gang Ye3, Can-dong Liu2, Wen-dong Xu2   

  1. 1 Department of Neurology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China 2 Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai, China 3 Department of Rehabilitation Medicine, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
  • Online:2016-07-30 Published:2016-07-30
  • Contact: Yan Chen, yanchenl@sina.com.
  • Supported by:
    This study was supported in part by the National Natural Science Foundation of China, No. 61108077.

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摘要：

低功率激光已经被应用于轻、中度的腕管综合征的非手术治疗中，但长期存在疗效有效性的争议。在激光治疗中，激光到达患处的相关激光参数与其导致的生物效应密切相关，要准确评价低功率激光治疗腕管综合征的有效性，必须准确测量和控制激光参数，这一点在过去临床试验中常被忽略。为此，我们研制了激光后向散射和反射测量装置，并结合商用半导体激光治疗仪首次开展了激光治疗腕管综合征患者30例的后向激光反射和散射的测量，以期得到激光治疗的有效激光功率参数。结果发现有效激光功率的患者个体差异较为显著，实测的激光反射率为1.8%-54.0%。不同反射系数在这30例患者中概率分布检测显示，37%的患者反射系数为10%-20%，有18%的患者的反射系数高于40%。实验成功检测并获得了激光治疗腕管综合征中的有效光功率参数，这对腕管综合征激光治疗时有效激光功率的监测是必要的。 

orcid: 0000-0002-0999-0819 (Yan Chen)

关键词: 神经再生, 周围神经再生, 腕管综合征, 激光治疗, 正中神经, 激光, 皮肤吸收, 皮肤反射, 散射, 激光参数, 激光功率测量, 光电二极管, 激光治疗, 正中神经, 皮肤吸收, 国家自然科学基金

Abstract: Low-power laser therapy has been used for the non-surgical treatment of mild to moderate carpal tunnel syndrome, although its efficacy has been a long-standing controversy. The laser parameters in low-power laser therapy are closely related to the laser effect on human tissue. To evaluate the efficacy of low-power laser therapy, laser parameters should be accurately measured and controlled, which has been ignored in previous clinical trials. Here, we report the measurement of the effective optical power of low-power laser therapy for carpal tunnel syndrome. By monitoring the backside reflection and scattering laser power from human skin at the wrist, the effective laser power can be inferred. Using clinical measurements from 30 cases, we found that the effective laser power differed significantly among cases, with the measured laser reflection coefficient ranging from 1.8% to 54%. The reflection coefficient for 36.7% of these 30 cases was in the range of 10–20%, but for 16.7% of cases, it was higher than 40%. Consequently, monitoring the effective optical power during laser irradiation is necessary for the laser therapy of carpal tunnel syndrome.

Key words: nerve regeneration, peripheral nerve regeneration, carpal tunnel syndrome, laser therapy, median nerve, diode laser, skin absorption, skin reflection, skin scattering, laser power measurement, laser therapy, neural regeneration