中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2013, Vol. 8 ›› Issue (20): 1829-1836.doi: 10.3969/j.issn.1673-5374.2013.20.001

• 原著:周围神经损伤修复保护与再生 •    下一篇

健康人颈部神经的三维数字可视化模型

  

  • 收稿日期:2012-12-27 修回日期:2012-12-27 出版日期:2013-07-15 发布日期:2013-07-15

A three-dimensional digital visualization model of cervical nerves in a healthy person

Jiaming Cao1, Dong Fu2, Sen Li3   

  1. 1 Department of Anesthesiology, the 98 Hospital of Chinese PLA, Huzhou 313000, Zhejiang Province, China
    2 Department of Surgery, Hospital of 8691 People’s Armed Police Force, Huzhou 313000, Zhejiang Province, China
    3 Department of Spinal Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China
  • Received:2012-12-27 Revised:2012-12-27 Online:2013-07-15 Published:2013-07-15
  • Contact: Dong Fu, M.D., Attending physician, Department of Surgery, Hospital of 8691 People’s Armed Police Force, Huzhou 313000, Zhejiang Province, China, gdfudong@126.com.
  • About author:Jiaming Cao, Master, Associate chief physician.

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摘要：

许多研究中三维重建神经模型取材于“可视人”冰冻切片二维图像，由于神经组织柔韧且与周围组织色彩差别小，在薄层铣切过程中会失去神经组织的完整性与真实性。鉴于此，实验取健康志愿者进行连续X射线电子计算机断层动脉造影和磁共振脊髓造影断面成像获得原始二维数据，以Mimics软件基于不同阈值对不同组织进行半自动分割和重建，以医学计算机辅助设计模块对颈部神经、肌肉等细小解剖结构进行重建，三维化显示颈部神经及周围相关局部解剖结构，建立的颈部神经相关结构三维可视化模型，可显示不同神经和周围相关解剖结构三维毗邻关系，立体感强、形态逼真、走形清晰，其连续性、精确性、完整性较好。说明实验成功构建了健康人颈部神经三维数字可视化模型，克服了薄层铣切技术的缺陷，避免了数据的缺失，图像失真度小，可从各角度观察到形态更真实，立体感更强的图像。

关键词: 神经再生, 颈, 三维, X射线计算机, 磁共振成像, 颈丛, 膈神经, 迷走神经, 喉返神经, 神经节, 星状神经节, 基金资助文章

Abstract:

Three-dimensional reconstruction nerve models are classically obtained from two-dimensional im-ages of “visible human” frozen sections. However, because of the flexibility of nerve tissues and small color differences compared with surrounding tissues, the integrity and validity of nerve tissues can be impaired during milling. Thus, in the present study, we obtained two-dimensional data from a healthy volunteer based on continuous CT angiography and magnetic resonance myelography. Semi-automatic segmentation and reconstruction were then conducted at different thresholds in different tissues using Mimics software. Small anatomical structures such as muscles and cervical nerves were reconstructed using the medical computer aided design module. Three-dimensional digital models of the cervical nerves and their surrounding structures were successfully developed, which allowed visualization of the spatial relation of anatomical structures with a strong three-dimensional effect, distinct appearance, clear distribution, and good continuity, precision, and integrality. These results indicate the validity of a three-dimensional digital visualization model of healthy human cervical nerves, which overcomes the disadvantages of milling, avoids data loss, and exhibits a realistic appearance and three-dimensional image.