中国神经再生研究(英文版) ›› 2016, Vol. 11 ›› Issue (8): 1274-1277.doi: 10.4103/1673-5374.189192

• 原著:脑损伤修复保护与再生 • 上一篇    下一篇

掌侧和背侧手夹板使用期间大脑皮质激活的差异:一项功能MRI研究

  

  • 出版日期:2016-08-31 发布日期:2016-08-31
  • 基金资助:
    韩国政府国家研究基金

Difference in cortical activation during use of volar and dorsal hand splints: a functional magnetic resonance imaging study

Sung Ho Jang, Woo Hyuk Jang *   

  1. Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daemyungdong, Namku, Daegu, South Korea
  • Online:2016-08-31 Published:2016-08-31
  • Contact: Woo Hyuk Jang, Ph.D., wlqtksek@hanmail.net.
  • Supported by:
    This work was supported by the National Research Foundation (NRF) of Korea Grant funded by the Korean Government (MSIP), No.2015R1A2A2A01004073.

摘要:

由于目前尚未见掌侧和背侧手夹板使用期间大脑皮质激活差异的研究,我们试图应用功能MRI对比观察掌侧与背侧手夹板使用期间大脑皮质激活的差异。试验纳入8名健康志愿者,让其佩戴掌侧或背侧手夹板,在其进行抓放运动时进行功能MRI检测。感兴趣区设置于初级运动皮质、初级体感皮质、后顶叶皮质、次级体感皮质。功能MRI数据的成组分析显示,佩戴掌侧手夹板者所有大脑皮质感兴趣区激活体素数量和激活程度明显多于/高于佩戴背侧手夹板者。这些数据为临床物理治疗师对不同类型手部功能损害患者进行神经康复治疗时,手夹板的应用选择提供了参考。

orcid: 0000-0002-7012-4565 (Woo Hyuk Jang)

关键词: 功能MRI, 手夹板, 体感功能, 掌侧手夹板, 背侧手夹板

Abstract: There have been no studies reported on the difference in cortical activation during use of volar and dorsal hand splints. We attempted to investigate the difference in cortical activation in the somatosensory cortical area during use of volar and dorsal hand splints by functional magnetic resonance imaging (fMRI). We recruited eight healthy volunteers. fMRI was performed while subjects who were ftted with volar or dorsal hand splints performed grasp-release movements. Regions of interest were placed on the primary motor cortex (M1), primary somatosensory cortex (S1), posterior parietal cortex (PPC), and secondary somatosensory cortex (S2). Results of group analysis of fMRI data showed that the total numbers of activated voxels in all ROIs were significantly higher during use of volar hand splint (3,376) compared with that (1,416) during use of dorsal hand splint. In each ROI, use of volar hand splint induced greater activation in all ROIs (M1: 1,748, S1 :1,455, PPC: 23, and S2: 150) compared with use of dorsal hand splint (M1: 783, S1: 625, PPC: 0, and S2: 8). The peak activated value was also higher during use of volar hand splint (t-value: 17.29) compared with that during use of dorsal hand splint (t-value: 13.11). Taken together, use of volar hand splint induced greater cortical activation relevant to somatosensory function than use of dorsal hand splint. This result would be important for the physiatrist and therapist to apply appropriate somatosensory input in patients with brain injury.

Key words: nerve regeneration, functional MRI, hand splint, somatosensory function, dorsal hand splint, volar hand splint, neural regeneration