毛囊干细胞和黑素干细胞在神经科学的应用

doi:10.3969/j.issn.1673-5374.2012.34.012

摘要/Abstract

摘要：

目的：探讨2002年~2011年毛囊干细胞和黑素干细胞及其在神经科的应用的研究动态。
设计：本文运用文献计量学在SCI数据库里分别分析了2002年~2011年毛囊干细胞和黑素干细胞及其在神经科的应用的研究动态，使用的关键词是毛囊干细胞、黑素干细胞和神经。
入选标准：纳入标准：(a) 在SCI数据库里检索与毛囊干细胞和黑素干细胞及其在神经科的应用相关的经同行评审的文献; (b) 文献类型包括：①研究原著。②会议文章。③综述。④快报。⑤编辑素材。⑥会议摘要。⑦复印版本。⑧勘误; (c)检索的文献限定在2002~2011时间范围内。排除标准：(a)需要手工检索或电话追踪的文献。(b)非公开发表的文献。(c)与文章目的无关的文献。
主要数据判定指标：(1) 毛囊干细胞和黑素干细胞相关文献的发表时间、来源期刊、国家地区分布、机构分布、中国机构分布、高被引文献分析。 (2) 毛囊干细胞和黑素干细胞在神经科的应用相关文献的发表时间、来源期刊、国家地区分布、机构分布、高被引文献分析。
结果：在我们分析的SCI数据库里毛囊干细胞和黑素干细胞研究方面的近10年的348篇文献中，美国作者或机构参与研究的超过一半。在这方面参与研究较多的中国机构是第四军医大学和第三军医大学，发表文献最多的杂志是《皮肤病学研究杂志》、《色素细胞和黑素瘤研究》和《细胞干细胞》。在我们分析的SCI数据库里毛囊干细胞和黑素干细胞在神经科的应用研究方面的这10年的63篇文献中，美国作者或机构参与研究的超过一半，没有中国作者或机构参与。在这方面发表文献最多的杂志是《皮肤病学研究杂志》、《色素细胞和黑素瘤研究》和《细胞周期》。
结论：经过对文献的分析，我们认为毛囊干细胞和黑素干细胞在再生医学里是非常有潜力的。

关键词: 皮肤干细胞, 毛囊干细胞, 黑素干细胞, 皮肤前体细胞, 神经嵴干细胞, 神经元, 神经胶质细胞, 分化, 文献计量学, 神经再生

Abstract:

OBJECTIVE: To identify global research trends of follicle and melanocyte stem cells, and their application in neuroscience.
DATA RETRIEVAL: We performed a bibliometric analysis of studies from 2002 to 2011 on follicle and melanocyte stem cells, and their application in neuroscience, which were retrieved from the Web of Science, using the key words follicle stem cell or melanocyte stem cell, and neural, neuro or nerve.
SELECTION CRITERIA: Inclusion criteria: (a) peer-reviewed published articles on follicle and melanocyte stem cells, and their application in neuroscience, which were indexed in the Web of Science; (b) original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items. Exclusion criteria: (a) articles that required manual searching or telephone access; (b) documents that were not published in the public domain; and (c) a number of corrected papers from the total number of articles.
MAIN OUTCOME MEASURES: (1) Distribution of publications on follicle and melanocyte stem cells by years, journals, countries, institutions, institutions in China, and most cited papers. (2) Distribution of publications on the application of follicle and melanocyte stem cells in neuroscience by years, journals, countries, institutions, and most cited papers.
RESULTS: Of the 348 publications from 2002 to 2011 on follicle and melanocyte stem cells, which were retrieved from the Web of Science, more than half were from American authors and institutes. The most prolific institutions in China for publication of papers on follicle and melanocyte stem cells were the Fourth Military Medical University and Third Military Medical University. The most prolific journals for publication of papers on follicle and melanocyte stem cells were the Journal of Investigative Dermatology, Pigment Cell & Melanoma Research. Of the 63 publications from 2002 to 2011 on the application of follicle and melanocyte stem cells in neuroscience, which were retrieved from the Web of Science, more than half were from American authors and institutes, and no papers were from Chinese authors and institutes. The most prolific journals for publication of papers on the application of follicle and melanocyte stem cells in neuroscience were the Journal of Investigative Dermatology, Pigment Cell & Melanoma Research.
CONCLUSION: Based on our analysis of the literature and research trends, we found that follicle stem cells might offer further benefits in neural regenerative medicine.

Key words: skin stem cell, follicle stem cell, melanocyte stem cell, skin-derived precursor, neural crest stem cell, neuron, glial cell, differentiation, bibliometric, neural regeneration

. 毛囊干细胞和黑素干细胞在神经科学的应用[J]. 中国神经再生研究(英文版), 2012, 7(34): 2734-2741.

Weifu Wu. Follicle and melanocyte stem cells, and their application in neuroscience A Web of Science-based literature analysis[J]. Neural Regeneration Research, 2012, 7(34): 2734-2741.

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引言

材料方法

Data retrieval

This study used bibliometric analyses to quantitatively and qualitatively investigate research trends of studies on follicle and melanocyte stem cells, and their application in neuroscience. We searched the Web of Science, a research database of publications and citations selected and evaluated by the Institute for Scientific Information in Philadelphia, PA, USA, using the keywords follicle stem cell or melanocyte stem cell, and neural, neuro or nerve. We limited the publication period from 2002 to 2011, and compiled a bibliography of all articles related to follicle melanocyte stem cells, and their application in neuroscience. We downloaded the data on September 4^th, 2012.

Inclusion criteria

The inclusion criteria are as follows: (1) published peer-reviewed articles on follicle and melanocyte stem cells, and their application in neuroscience, including original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items, which were indexed in the Web of Science; (2) the years of publication were 2002–2011; and (3) the citation database was Science Citation Index Expanded.

Exclusion criteria

We excluded articles that required manual searching or telephone access, documents that were not published in the public domain, and a number of corrected papers from the total number of articles analyzed.

The outcomes of all articles referring to skin stem cells were assessed using the following criteria. (a) Annual publication output of papers on follicle and melanocyte stem cells. (b) Distribution of publications on follicle and melanocyte stem cells by journals. (c) Distribution of publications on follicle and melanocyte stem cells by countries. (d) Distribution of publications on follicle and melanocyte stem cells by institutions. (e) Distribution of publications on follicle and melanocyte stem cells by institutions in China. (f) Most cited papers on follicle and melanocyte stem cells in the Web of Science from 2002 to 2011. (g) Annual publication output of papers on the application of follicle and melanocyte stem cells in neuroscience. (h) Distribution of publications on the application of follicle and melanocyte stem cells in neuroscience by journals. (i) Distribution of publications on the application of follicle and melanocyte stem cells in neuroscience by countries. (j) Distribution of publications on the application of follicle and melanocyte stem cells in neuroscience by institutions. (k) Most cited papers on the application of follicle and melanocyte stem cells in neuroscience in the Web of Science from 2002 to 2011.