中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2013, Vol. 8 ›› Issue (14): 1269-1275.doi: 10.3969/j.issn.1673-5374.2013.14.003

• 原著:周围神经损伤修复保护与再生 • 上一篇    下一篇

正常中国人尸体坐骨神经与人羊膜黏弹性的比较

  

  • 收稿日期:2012-08-10 修回日期:2013-01-10 出版日期:2013-05-15 发布日期:2013-05-15

Comparison of viscoelasticity between normal human sciatic nerve and amniotic membrane

Donghui Xu1, Conghai Zhao1, Huili Ma2, Jun Wei1, Dongyuan Li1   

  1. 1 Department of Neurosurgery, China-Japan Union Hospital, Jilin University, Changchun 130031, Jilin Province, China
    2 Department of Road & Bridge, College of Transportation, Jilin University, Changchun 130022, Jilin Province, China
  • Received:2012-08-10 Revised:2013-01-10 Online:2013-05-15 Published:2013-05-15
  • Contact: Dongyuan Li, Associate chief physician, Department of Neurosurgery, China-Japan Union Hospital, Jilin University, Changchun 130031, Jilin Province, China, Lidy@jiu.edu.cn.
  • About author:Donghui Xu★, Master, Attending physician.

PDF

897

摘要：

取正常中国人新鲜尸体臀大肌段坐骨神经试样和健康产妇胎盘的羊膜试样，分别进行应力松弛和蠕变实验检测后发现，人羊膜和坐骨神经试样应力-松弛、蠕变变化趋势相似。人羊膜应力松弛组7 200 s应力下降量大于正常坐骨神经应力松弛组，人羊膜蠕变组7 200 s应变上升量大于正常坐骨神经蠕变组。人羊膜与坐骨神经的应力松弛曲线呈对数关系变化的，蠕变曲线是以指数关系变化。说明正常中国人羊膜较坐骨神经具有更好的应力松弛、蠕变特性。

关键词: 神经再生, 尸体, 人, 坐骨神经, 人羊膜, 应力松弛, 蠕变, 黏弹性, 应力, 生物力学, 神经组织工程

Abstract:

Sciatic nerve tissue was obtained from the gluteus maximus muscle segment of normal human cadavers and amniotic membrane tissue was obtained from healthy human puerperant placentas. Both tissues were analyzed for their stress relaxation and creep properties to determine suitability for transplantation applications. Human amniotic membrane and sciatic nerve tissues had similar tendencies for stress relaxation and creep properties. The stress value of the amniotic membrane stress relaxation group decreased to a greater extent compared with the sciatic nerve stress relaxation group. Similarly, the stress value of the amniotic membrane creep group increased to a greater extent compared with the sciatic nerve creep group. The stress relaxation curve for human amniotic membrane and sciatic nerve showed a logarithm correlation, while the creep curve showed an exponential correlation. These data indicate that amniotic membrane tissue has better stress relaxation and creep properties compared with sciatic nerve tissue.

Key words: neural regeneration, basic research, cadaver, human, sciatic nerve, amniotic membrane, stress relaxation, creep, viscoelasticity, stress, biomechanics, nerve tissue engineering, neuroregeneration