中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2013, Vol. 8 ›› Issue (34): 3249-3254.doi: 10.3969/j.issn.1673-5374.2013.34.009

• 原著:脑损伤修复保护与再生 • 上一篇    下一篇

胎儿脐静脉移植可用于大脑中动脉损伤的修复

  

  • 收稿日期:2013-09-27 修回日期:2013-11-08 出版日期:2013-12-05 发布日期:2013-12-05

Fetal umbilical vein transplantation for the repair of middle cerebral artery injury

Xuhui Hou1, Yi Yuan1, Jian Yin1, Songbai Yang1, Lili Xie1, Shiji Wang2   

  1. 1 Department of Vascular Surgery, China-Japan Friendship Hospital of Jilin University, Changchun 130031, Jilin Province, China
    2 Department of Critical Care Medicine, First Hospital of Jilin University, Changchun 130021, Jilin Province, China
  • Received:2013-09-27 Revised:2013-11-08 Online:2013-12-05 Published:2013-12-05
  • Contact: Shiji Wang, Ph.D., Associate chief physician, Department of Critical Care Medicine, First Hospital of Jilin University, Changchun 130021, Jilin Province, China, wsj@jlu.edu.cn.
  • About author:Xuhui Hou, Ph.D., Associate chief physician.

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摘要：

若能以胎儿脐静脉移植修复损伤大脑中动脉，有必要搞清楚大脑中动脉与胎儿脐静脉的纵向拉伸力学特性有无区别。实验采集新鲜胎儿脐静脉、正常人新鲜尸体大脑中动脉各15个试样，在人体正常体温下以0.5mm/min的速度对试样施加拉伸载荷。实验结果表明，当对2组试样施加的应力为生理应力16.0kPa时，胎儿脐静脉的应变值大于大脑中动脉组，而最大应力、弹性模量值均小于大脑中动脉组。说明胎儿脐静脉具有很好的弹性特性，且其应力应变曲线和大脑中动脉相似，因而提示在生物力学上胎儿脐静脉可以替代大脑中动脉用于移植大脑中动脉损伤的修复。

中国神经再生研究（英文版）杂志出版内容重点： 脑损伤；脊髓损伤；周围神经损伤；帕金森；神经影像；神经再生

关键词: 神经再生, 大脑中动脉, 胎儿脐静脉, 拉伸, 应力, 应变, 弹性模量, 生物力学, 移植修复, 再生