中国神经再生研究(英文版) ›› 2014, Vol. 9 ›› Issue (3): 280-284.doi: 10.4103/1673-5374.128223

• 原著:脑损伤修复保护与再生 • 上一篇    下一篇

健康成人大脑视放射纤维束定量容积:弥散张量成像分析

  

  • 收稿日期:2013-11-25 出版日期:2014-02-15 发布日期:2014-02-15

Quantitative volumetric analysis of the optic radiation in the normal human brain using diffusion tensor magnetic resonance imaging-based tractography

Dong-Hoon Lee1, 2, Ji-Won Park3, Cheol-Pyo Hong1   

  1. 1 Center for Medical Metrology, Division of Convergence Technology, Korea Research Institute of Standards and Science (KRISS), Daejeon,
    Republic of Korea
    2 Department of Radiological Science, College of Health Science, Yonsei University, Wonju, Republic of Korea
    3 Department of Physical Therapy, College of Medical Science, Catholic University of Daegu, Daegu, Republic of Korea
  • Received:2013-11-25 Online:2014-02-15 Published:2014-02-15
  • Contact: Cheol-Pyo Hong, Ph.D., 267 Gajeong-Ro, Yuseong-Gu, Daejeon 305-340, Republic of Korea, dosagehong@kriss.re.kr.

摘要:

为得获得健康成人大脑视放射容积数据,我们对13例健康成人进行DTI检查。同时我们还应用了大脑标化方法,以减少个体大脑差异,提高容积数据检测的准确性;应用基于纤维束组图方法,以研究视放射通路的概率和分布。结果显示,健康人成人视放射纤维束体积约为0.16%,各向异性值约为0.53。基于DTT组图检测的OR概率纤维通路可相对准确地定位OR。实验结果为研究成人大脑视觉通路定量和解剖结构提供了临床数据。

关键词: 神经再生, 视放射, 弥散张量成像, 弥散张量纤维束成像, MRI, 容积分析, 概率通路图, 组图, 可视化, 个体差异

Abstract:

o attain the volumetric information of the optic radiation in normal human brains, we performed diffusion tensor imaging examination in 13 healthy volunteers. Simultaneously, we used a brain normalization method to reduce individual brain variation and increase the accuracy of volumetric information analysis. In addition, tractography-based group mapping method was also used to investigate the probability and distribution of the optic radiation pathways. Our results showed that the measured optic radiation fiber tract volume was a range of about 0.16% and that the fractional anisotropy value was about 0.53. Moreover, the optic radiation probability fiber pathway that was determined with diffusion tensor tractography-based group mapping was able to detect the location relatively accurately. We believe that our methods and results are helpful in the study of optic radiation fiber tract information.