中国神经再生研究(英文版) ›› 2017, Vol. 12 ›› Issue (4): 660-670.doi: 10.4103/1673-5374.205108

• 综述:退行性病与再生 • 上一篇    下一篇

植物药可改善阿尔茨海默病及记忆功能障碍

  

  • 收稿日期:2017-03-29 出版日期:2017-04-15 发布日期:2017-04-15

Effects of medicinal plants on Alzheimer’s disease and memory deficits

Muhammad Akram1, Allah Nawaz2   

  1. 1 Department of Eastern Medicine and Surgery, Faculty of Medical and Health Sciences, The University of Poonch, Rawalakot, Azad Jammu and Kashmir, Pakistan; 2 First Department of Internal Medicine, Faculty of Medicine, University of Toyama, Toyama, Japan
  • Received:2017-03-29 Online:2017-04-15 Published:2017-04-15
  • Contact: Muhammad Akram, M.D., Ph.D., makram_0451@yahoo.com; makram_0451@hotmail.com.

摘要:

阿尔茨海默病是以渐进性记忆功能障碍为特征的年龄相关性神经变性疾病,目前的治疗方法只能是对症治疗。传统植物药长久以来即作为记忆增强剂在世界范围内广泛应用,被用于治疗记忆功能障碍性疾病,如痴呆、遗忘症以及阿尔茨海默病,植物药在不同的医药体系中都有所应用。特别是波斯阿拉伯的Unani传统医药体系中,植物药在记忆障碍的治疗中表现出强大的作用,但其作用机制仍有待进一步研究。文章总结了植物药在包括阿尔茨海默病在内的记忆功能障碍性疾病中的治疗作用。

ORCID:0000-0001-7863-8803(Muhammad Akram)

关键词: 神经再生, 阿尔茨海默病, 记忆, 药物植物, 神经退行性疾病, 传统医药, 综述

Abstract:

Alzheimer’s disease is an age-related neurodegenerative disorder characterized by memory deficits. Various studies have been carried out to find therapeutic approaches for Alzheimer’s disease. However, the proper treatment option is still not available. There is no cure for Alzheimer’s disease, but symptomatic treatment may improve the memory and other dementia related problems. Traditional medicine is practiced worldwide as memory enhancer since ancient times. Natural therapy including herbs and medicinal plants has been used in the treatment of memory deficits such as dementia, amnesia, as well as Alzheimer’s disease since a long time. Medicinal plants have been used in different systems of medicine, particularly Unani system of medicines and exhibited their powerful roles in the management and cure of memory disorders. Most of herbs and plants have been chemically evaluated and their efficacy has also been proven in clinical trials. However, the underlying mechanisms of actions are still on the way. In this paper, we have reviewed the role of different medicinal plants that play an important role in the treatment of Alzheimer’s disease and memory deficits using conventional herbal therapy.

Key words: nerve regeneration, memory, Alzheimer’s disease, medicinal plants, efficacy, literature review, neural regeneration