中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2013, Vol. 8 ›› Issue (11): 1041-1047.doi: 10.3969/j.issn.1673-5374.2013.11.010

• 综述:周围神经损伤修复保护与再生 • 上一篇    下一篇

周围神经卡压伤后的神经微循环改变

  

  • 收稿日期:2012-10-12 修回日期:2013-02-10 出版日期:2013-04-15 发布日期:2013-04-15

Changes in nerve microcirculation following peripheral nerve compression

Yueming Gao1, Changshui Weng2, Xinglin Wang1   

  1. 1 Rehabilitation Medicine Center, General Hospital of Chinese PLA, Beijing 100853, China
    2 Department of Rehabilitation Medicine, South Building, General Hospital of Chinese PLA, Beijing 100853, China
  • Received:2012-10-12 Revised:2013-02-10 Online:2013-04-15 Published:2013-04-15
  • Contact: Xinglin Wang, M.D., Chief physician, Professor, Rehabilitation Medicine Center, General Hospital of Chinese PLA, Beijing 100853, China, wxl0620@sina.com.
  • About author:Yueming Gao☆, M.D. Yueming Gao and Changshui Weng contributed equally to this work.

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摘要：

周围神经卡压伤后，神经再生的微环境、血氧供应、神经营养以及维持神经传导功能和轴突物质转运等具有重要作用。我们通过回顾近年来国内外关于周围神经卡压伤与神经微循环改变关系的相关文献，认为周围神经在人体分布广泛，不同部位神经卡压性疾病的症状各不相同，但发病机制均为神经受压后造成神经机械性损伤和微循环发生改变，从而引起轴突、髓鞘损伤、瘢痕及纤维化的形成，最终导致相应的神经症状。周围神经微循环结构、血供、神经内血管吻合支的密度、再生过程中血流的改变及不同压力及时间对于压迫周围神经损伤的影响与身体其他组织微循环有明显差异。

关键词: 神经再生, 围神经损伤, 围神经, 循环, 经卡压, 经血流量, 骨神经, 金资助文章

Abstract:

Following peripheral nerve compression, peripheral nerve microcirculation plays important roles in regulating the nerve microenvironment and neurotrophic substances, supplying blood and oxygen and maintaining neural conduction and axonal transport. This paper has retrospectively analyzed the articles published in the past 10 years that addressed the relationship between peripheral nerve compression and changes in intraneural microcirculation. In addition, we describe changes in different peripheral nerves, with the aim of providing help for further studies in peripheral nerve microcirculation and understanding its protective mechanism, and exploring new clinical methods for treating peripheral nerve compression from the perspective of neural microcirculation.

Key words: neural regeneration, eripheral nerve injury, eripheral nerve, icrocirculation, erve compression, erve blood flow, ciatic nerve, grants-supported paper, euroregeneration