中国神经再生研究(英文版)

中国神经再生研究(英文版) ›› 2013, Vol. 8 ›› Issue (30): 2856-2867.doi: 10.3969/j.issn.1673-5374.2013.30.008

• 综述:退行性病与再生 • 上一篇    下一篇

脑深部电刺激后的帕金森病患者：对社会适应不佳的理解

  

  • 收稿日期:2013-04-15 修回日期:2013-04-15 出版日期:2013-10-25 发布日期:2013-10-25

Neurosurgery in Parkinson’s disease: Social adjustment, quality of life and coping strategies

Meyer Mylène1, 2, 3, 4, Montel Sébastien1, 4, Colnat-Coulbois Sophie5, Lerond Jérôme6, Potheegadoo Jevita7, Vidailhet Pierre7, Gospodaru Nicolaie2, Vespignani Hervé1, 2, Barroche Gérard2, Spitz Elisabeth1, 4, Schwan Raymund1, 3, 8   

  1. 1 Lorraine University, Metz 57000, France
    2 Department of Neurology, University Hospital, Nancy 54000, France
    3 INSERM, Clinical Investigation Center 9501, Vandoeuvre-les-Nancy 54500, France
    4 Department of Health Psychology EPSAM, EA 4360 APEMAC, Metz 57000, France
    5 Department of Neurosurgery, University Hospital, Nancy 54000, France
    6 Psychotherapic Center of Nancy, Laxou 54520, France
    7 INSERM 666 Unit, University Hospital, Strasbourg 67000, France
    8 Care, Support and Prevention Center in Addiction, University Hospital, Nancy 54000, France
  • Received:2013-04-15 Revised:2013-04-15 Online:2013-10-25 Published:2013-10-25
  • Contact: Meyer Mylène, Neuropsychologist, CHU de Nancy-H?pital Central-Service de neurologie, 29 avenue du maréchal de Lattre de Tassigny, 54001 Nancy Cedex, France, my.meyer@chu-nancy.fr.

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摘要：

丘脑底核脑深部电刺激可明显改善帕金森病的运动症状，已成为治疗晚期帕金森病的常规方法。但因其对生活质量评估中的心理维度和社会适应方面无明显改善作用，甚至会使其变得更糟，故术前患者及家庭需要充分认识丘脑底核脑深部电刺激能够改变患者运动状态及生活环境哪些问题。文章综述了双侧丘脑底核脑深部电刺激对帕金森病患者社会适应、生活质量和应对策略的影响，从而帮助人们理解丘脑底核脑深部电刺激使帕金森病患者出现的社会心理失调和生活质量改善不佳的现象。

关键词: 神经再生, 综述, 神经退行性疾病, 帕金森病, 丘脑底核, 电刺激, 脑深部电刺激, 生活质量, 应对, 社会适应

Abstract:

Subthalamic nucleus deep brain stimulation has become a standard neurosurgical therapy for ad-vanced Parkinson’s disease. Subthalamic nucleus deep brain stimulation can dramatically improve the motor symptoms of carefully selected patients with this disease. Surprisingly, some specific dimensions of quality of life, “psychological” aspects and social adjustment do not always improve, and they could sometimes be even worse. Patients and their families should fully understand that subthalamic nucleus deep brain stimulation can alter the motor status and time is needed to readapt to their new postoperative state and lifestyles. This paper reviews the literatures regarding effects of bilateral subthalamic nucleus deep brain stimulation on social adjustment, quality of life and coping strategies in patients with Parkinson’s disease. The findings may help to understand the psychoso-cial maladjustment and poor improvement in quality of life in some Parkinson’s disease patients.

Key words: neural regeneration, Parkinson’s disease, subthalamic nucleus, deep brain stimulation, quality of life, coping, social adjustment, reviews, neurodegenerative diseases