中国神经再生研究(英文版) ›› 2014, Vol. 9 ›› Issue (7): 712-718.doi: 10.4103/1673-5374.131574

• 观点:脑损伤修复保护与再生 • 上一篇    下一篇

大脑运动皮质神经元接受非侵袭性磁或电刺激的干预:改善了什么

  

  • 收稿日期:2014-03-06 出版日期:2014-04-15 发布日期:2014-04-15
  • 基金资助:

    西班牙La Marató TV3基金(PI110931)

Outcomes in spasticity after repetitive transcranial magnetic and transcranial direct current stimulations

Aysegul Gunduz 1, Hatice Kumru 2, 3, 4, Alvaro Pascual-Leone 5   

  1. 1 Department of Neurology, Cerrahpasa School of Medicine, Istanbul University, Istanbul, Turkey
    2 Institut Guttmann, Institut Universitari de Neurorehabilitació adscrit a la UAB, Badalona, Barcelona, Spain
    3 Universitat Autonoma de Barcelona, 08193 Bellaterra (Cerdanyola del Vallès), Spain
    4 Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona, Spain
    5 Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
  • Received:2014-03-06 Online:2014-04-15 Published:2014-04-15
  • Contact: Hatice Kumru, M.D., Ph.D., Hospital de Neurorehabilitació Institut Guttmann, Camí Can Ruti s/n. Barcelona, 08916 Barcelona, Spain, hkumru@guttmann.com.
  • Supported by:

    This work was supported in part by grants from Foundation La Marató TV3. No. PI110932.

摘要:

非侵袭性大脑刺激主要包括重复经颅磁刺激和经颅电刺激。重复经颅磁刺激在改善多发性硬化、脑卒中、脊髓损伤和脑性瘫痪导致的痉挛状态方面体现出了良好的效果。经颅电刺激主要用于改善脑卒中后的痉挛状态。为了更好地验证非侵袭性大脑刺激改善痉挛状态的有效性,需要有更多大样本前瞻性队列研究加以证实。

关键词: 神经再生, 综述, 痉挛, 运动皮质, 经颅磁刺激, 经颅电刺激, 中枢神经系统, 脑卒中, 西班牙La Marató, TV3基金

Abstract:

Non-invasive brain stimulations mainly consist of repetitive transcranial magnetic stimulation and transcranial direct current stimulation. Repetitive transcranial magnetic stimulation exhibits satisfactory outcomes in improving multiple sclerosis, stroke, spinal cord injury and cerebral  palsy-induced spasticity. By contrast, transcranial direct current stimulation has only been studied in post-stroke spasticity. To better validate the efficacy of non-invasive brain stimulations in improving the spasticity post-stroke, more prospective cohort studies involving large sample sizes are needed.

Key words: reviews, muscle spasticity, motor cortex, transcranial magnetic stimulation, transcranial direct current stimulation, central nervous system, stroke