中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (2): 375-381.doi: 10.4103/1673-5374.290909

• 原著:颅神经损伤修复保护与再生 • 上一篇    下一篇

呼吸训练和声音音调治疗对改善脊髓损伤患者呼吸功能和声音质量的有效性:随机对照试验

  

  • 出版日期:2021-02-15 发布日期:2020-12-04
  • 基金资助:
    中国康复研究中心科研基金项目(2019zx-23),北京市自然科学基金项目(7192238)

Effectiveness of oral motor respiratory exercise and vocal intonation therapy on respiratory function and vocal quality in patients with spinal cord injury: a randomized controlled trial

Xiao-Ying Zhang1, 2, 3, 4, 5, Yi-Chuan Song1, 5, Chang-Bin Liu1, 2, 3, 4, 6, Chuan Qin1, 2, 3, 4, 7, Song-Huai Liu1,  5, Jian-Jun Li1, 2, 3, 4, 7, *   

  1. 1 School of Rehabilitation Medicine, Capital Medical University, Beijing, China;  2 China Rehabilitation Science Institute, Beijing, China;  3 Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing, China;  4 Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing, China;  5 Music Therapy Center, Department of Psychology, China Rehabilitation Research Center, Beijing, China;  6 Department of Rehabilitation Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China;  7 Department of Spinal and Neural Functional Reconstruction, China Rehabilitation Research Center, Beijing, China
  • Online:2021-02-15 Published:2020-12-04
  • Contact: Jian-Jun Li, MD, crrclijj@163.com.
  • Supported by:
    This work was supported by Scientific Research Foundation of China Rehabilitation Research Center, No. 2019zx-23 (to SHL) and the Natural Science Foundation of Beijing of China, No. 7192238.

摘要:

歌唱作为一种结合呼吸训练和声音治疗的新方法,为脊髓损伤患者呼吸功能的训练开辟了新方向。此次随机对照研究探讨了口腔运动呼吸训练和声音治疗对脊髓损伤患者呼吸功能和声音质量的影响。共招募了31例脊髓损伤患者,其中18例完成了治疗。这18例患者随机进行音乐疗法和口腔运动呼吸训练(干预组,n = 9;7男2女;30.33±11.74岁)或单纯正常呼吸训练(对照组,n = 9;8男1女;34.78±11.13岁)。干预组行30min/d,5次/周,共12周的口腔运动呼吸训练和声音治疗。2组患者均同时接受常规治疗。在干预前、干预后6和12周时,测量标准呼吸功能测试、声音测试和圣乔治呼吸调查问卷以及生活质量问卷评分。结果显示,与对照组相比,干预组呼吸功能中的吸气量、1s用力呼气量、用力肺活量、最大呼气中流量明显增加,且声压水平和持续音长度也显著增加。同时干预组St. George呼吸问卷和生活质量量表评分结果均优于对照组。表明口腔运动呼吸训练和声音治疗可作为音乐疗法中的歌唱呼吸训练的方法,对于改善脊髓损伤患者的呼吸功能障碍和声音质量是有效且有价值的。研究于2019年5月27日经中国康复研究中心伦理委员会批准,批准号2019-78-1,并于2019年10月26日在中国临床试验注册中心注册,注册号:ChiCTR1900026922。

https://orcid.org/0000-0002-6329-2958 (Xiao-Ying Zhang); 

https://orcid.org/0000-0002-8441-7537 (Jian-Jun Li)

关键词: 中枢神经, 脊髓, 损伤, 修复, 呼吸训练, 口腔运动, 随机对照, 临床试验

Abstract: Singing, as a method of combining respiratory function exercise and vocal intonation therapy, provides a new direction for respiratory function exercise in patients with spinal cord injury. This randomized controlled trial investigated the effects of oral motor respiratory exercise and vocal intonation therapy on respiratory function and vocal quality in patients with spinal cord injury. Among 31 included patients with spinal cord injury, 18 completed the treatment. These 18 patients were randomly assigned to undergo music therapy (intervention group, 30 min/d, 5 times a week, for a total of 12 weeks; n = 9, 7 males and 2 females; 30.33 ± 11.74 years old) or normal respiratory training (control group, n = 9; 8 males and 1 female; 34.78 ± 11.13 years old). Both patient groups received routine treatment concurrently. Before and at 6 and 12 weeks after intervention, a standard respiratory function test, a voice test, the St. George’s Respiratory Questionnaire, and a quality of life questionnaire were administered. The results showed that the inspiratory capacity, forced expiratory volume in 1 second, forced vital capacity, maximal mid-expiratory flow rate, sing-loud pressure level, and sustained note length were significantly increased in the intervention group compared with the control group. The St. George’s Respiratory Questionnaire and quality of life results of patients in the intervention group were significantly superior to those in the control group. These findings suggest that oral motor respiratory exercise and vocal intonation therapy, as respiratory training methods in music therapy, are effective and valuable for improving respiratory dysfunction and vocal quality in patients with spinal cord injury. This study was approved by the Ethics Committee of China Rehabilitation Research Center (approval No. 2019-78-1) on May 27, 2019 and was registered with the Chinese Clinical Trial Registry (registration number: ChiCTR1900026922) on October 26, 2019. 

Key words: central nervous system, clinical trial, injury, oral motor, randomized, repair, respiratory exercise, spinal cord